DETERMINATION OF UROPEPSIN IN URINE IN IRON DEFICIENCY ANAEMIA IN EARLY CHILDREN AND ITS SIGNIFICANCE

Abstract

Annotation.  WHO  data  according  to,  every  1.5  billion  per  year  more  than 
anemia with patients to list is taken, almost 50% of cases iron shortage with related to 
UNICEF's Micronutrient Initiative iron shortage anemia to work of competence serious 
decline,  mothers  of  death  increase,  child  physical  and  mental  to  develop  negative 
impact to show such as economic importance has was factors between dependency 
shows . This and iron shortage anemia diagnosis early in the making various kind 
diagnostic methods question In children blood in diseases urine in the composition 
uropipsin amount determination less learned because of , we iron shortage anemia there 
is in children him/her to determine current that We knew . The work purpose so , 
anemia weight to the level related in the case in urine uropepsin Definition . Materials 
and methods . From 1 to 3 years old was every kind severe iron deficiency anemia 42 
children were examined . Stomach fermentative function in urine issued uropepsin 
amount with Pepsinogen stomach mucus on the floor working will be issued and to the 
blood  decreased  by  1%  urine  with  uropepsin  in  appearance  Research  for  morning 
issued from urine last second part taken, its amount and first and second pee between 
past time record The patient was in children in urine uropepsin amount anemia weight 
level into account received without Iron deficiency was detected . in anemia in urine 
uropepsin  amount  decrease  was  shown.  Even  light  level  uropepsin  also  in  anemia 
amount in urine healthy was to children than much lower (P <0.001 ) was detected in 
urine  uropepsin level study analysis this showed that his decrease anemia weight level 
increase parallel to . The lowest figures average and heavy level in anemia determined 
that is - up to 0.422 units per hour , ( normally 3.696 units per hour ). On average of 
the disease heavy at the level of 2.8 ± 0.51 units hour , and the norm is 7.46 ± 0.40 
units organization Clinical recovery on time come , anemia with sick children's in most 
cases 56.3% in urine uropepsin amount to normal values a little closer indicated , while 
in 43.7% of patients indicators normalization trend observed , but not completely to 
the norm did not come close . In the urine uropepsin of the composition normalization 
of the disease weight to the level related was : it is light at the level sick in patients 
complete restored if , average and especially heavy at the level sick in patients this 
indicator , norm relatively as little as possible saved.