CURRENT TUBERCULOSIS A IN HIV-INFECTED PATIENTS

Authors

  • Kholiev Bakhodir Oltibayevich Author

Keywords:

Key words: phthisiology, tuberculosis, HIV infection, Mycobacterium tuberculosis, immunosuppression, clinical manifestations, treatment.

Abstract

Summary: 
            Tuberculosis is widespread in all regions of the world. According to WHO, in 
2016, 476,774 people with tuberculosis had a positive HIV status, which accounted for 
7.5% of all reported cases. In 2016, more than 374,000 people living with HIV died 
from  tuberculosis  worldwide  (WHO,  2017).  In  recent  years,  the In  the  Russian 
Federation, there is a steady increase in the incidence of tuberculosis in patients with 
HIV infection. According to the Federal Tuberculosis Monitoring Center, the number 
of people living with HIV infection has doubled. The article provides an overview of 
the  epidemic  indicators  of  tuberculosis  and  HIV  infection  in  Russia. Problems  of 
diagnosis of tuberculosis in combination withcoinfection, as well as new laboratory 
and  immunological  methods  used  today  in  the  world  and  domestic  practice  to 
determine tuberculosis infection.  

References

Literature

1. Alekseeva L. P. Features of detection, clinical course and treatment of patients with

tuberculosis and HIV infection. Abstract of the thesis. ... Candidate of Medical

Sciences, Moscow, 2008; 43 p.

2. Belyakova N. V. Improvement of tuberculosis prevention in HIV-infected patients

in penitentiary institutions. Abstract of the thesis. ... Candidate of Medical

Sciences, Moscow, 2011; 26 p.

3. Borovitsky V. S. Roentgenological picture of pulmonary tuberculosis combined

with HIV infection in patients in a medical institution of the Federal Penitentiary

Service. – 2018; 1: 66–7.

4. Zimina V. N. Improving the diagnosis and effectiveness of tuberculosis treatment

in patients with HIV infection with various degrees of immunosuppression.

Abstract of the thesis. ... Doctor of Medical Sciences, Moscow, 2012; 45 p.

5. Ivanov A. K., Shevyreva E. V., Skrynnik N. A. et al. Treatment of patients with

tuberculosis and HIV infection in a day hospital of an antitubercular dispensary.

Proceedings of the X Annual All-Russian Congress on Infectious Diseases with

International participation, Moscow, 2018; p. 82.

6. Oblokulov A.A., Oblokulov A.R., Ergashov M.M. Clinical and laboratory criteria

for spontaneous bacterial peritonitis in liver cirrhosis of viral etiology. Central

Asian journal of medical and natural sciences Volume 03, Issue 03, may-jun 2022

172-177. ISSN: 2660-4159.

7. Abdulloev Mukhriddin Ziyodulloevich. (2023). Modern Therapy of Viral

Hepatitis. Texas Journal of Medical Science, 26, 66–69. Retrieved from

https://www.zienjournals.com/index.php/tjms/article/view/4636 9. Oblokulov R.

8. A., Abdulloev M. Z. To Study the Effectiveness of Direct-Antiviral Drug in the

Treatment of Chronic Viral Hepatitis C, Your Act //Web of Scholars:

Multidimensional Research Journal. – 2022. – Т. 1. – №. 5. – С. 201-206.

9. Ziyodulloyevich A. M. IN CHRONIC VIRAL HEPATITIS AND CIRRHOSIS OF

THE LIVER, THE STUDY OF CYTOKINE LEVELS //BARQARORLIK VA

YETAKCHI TADQIQOTLAR ONLAYN ILMIY JURNALI. – 2022. – Т. 2. – №.

12. - pp. 784-787.

10. Ziyodulloevich A. M. EFFICIENCY OF ETIOTROPIC TREATMENT IN

CHRONIC VIRAL HEPATITIS //Galaxy International Interdisciplinary Research

Journal. – 2023. – Т. 11. – №. 4. – С. 450-454.

11. Ziyodullayevich A. M. Studies on the Determination of Cytokines in Patients with

Chronic Hepatitis C with Criglobulinemia //American Journal of Pediatric

Medicine and Health Sciences (2993-2149). – 2023. – Т. 1. – №. 10. – С. 487-495.

12. Salina T. Yu., Morozova T. I. Clinical manifestations and effectiveness of

treatment of patients with coinfection with tuberculosis / HIV infection and

hepatitis / / Tuberculosis and lung diseases. – 2017; 95 (9): 25-9. DOI:

10.21292/2075-1230- 2017-95-9-25-29.

13. Galkin V. G., Elenkina Zh. V., Epifantseva N. A. et al. TB/HIV in the Russian

Federation. Epidemiology, features of clinical manifestations and treatment results.

Edited by S. A. Sterlikov / Moscow: RIO TSNIIOIZ, 2017; 52 p.

14. Fomenkova N. V. Clinical and laboratory characteristics of HIV infection in

combination with various forms of tuberculosis. Dis. ... candidate of Medical

Sciences. St. Petersburg, 2004; 140 p.

15. Frolova O. P., Kravchenko A. B., Martynov A. A. et al. Organization of TB care

for patients with HIV infection. Manual for doctors / M., Tver: OOO "Publishing

House "Triada", 2007; 120 p.

16. Shchelkanova A. I. Features of the clinical course and effectiveness of tuberculosis

chemotherapy in HIV-infected individuals. Abstract of the thesis.. дис ...

Candidate of Medical Sciences, Moscow, 2003; 24 p.

17. Beyrer C., Wirtz A., O'Hara G. et al. The expanding epidemic of HIV-1 in the

Russian Federation // PLoS Med. – 2017; 14 (11): e1002462. https://doi.

org/10.1371/journal.pmed.1002462.

18. Ellis P., Martin W., Dodd P. CD4 count and tuberculosis risk in HIV-positive

adults not on ART: a systematic review and meta-analysis // Peer J. – 2017; 5:

e4165. DOI: 10.7717/peerj.4165. 19. Isaakidis P., Casas E., Das M. et al.

Treatment outcomes for HIV and MDR-TB co-infected adults and children:

systematic review and meta-analysis. // Int. J. Tuberc. Lung Dis. – 2015;

19. (8): 969–78. http://dx.doi.org/10.5588/ ijtld.15.0123.

20. Kistana J., Lahera F., Otwombea K. et al. Pulmonary TB: varying radiological

presentations in individuals with HIV in Soweto, South Africa // Trans. R. Soc.

Trop. Med. Hyg. – 2017; 111: 132–6. DOI: 10.1093/trstmh/trx028.

21. Lawn S., Myer L., Bekker L. et al. Tuberculosis-associated immune reconstitution

disease: incidence, risk factors and impact in an antiretroviral treatment service in

South Africa // AIDS. – 2007; 21: 335–41.

22. Mahtab S., Coetzee D. Influence of HIV and other risk factors on tuberculosis // S.

Afr. Med. J. – 2017; 107 (5): 428–34. DOI: 10.7196/SAMJ.2017. v107i5.11271.

23. Murray J., Sonnenberg P., Shearer S. et al. Human immunodeficiency virus and

the outcome of treatment for new and recurrent pulmonary tuberculosis in African

patients // Am. J. Respir. Crit. Care. Med. – 1999; 159 (3): 733–40.

24. Nglazi M., Bekker L.-G., Wood R. et al. The impact of HIV status and

antiretroviral treatment on TB treatment outcomes of new tuberculosis patients

attending collocated TB and ART services in South Africa: a retrospective cohort

study // BMC Infect. Dis. – 2015; 15: 536. DOI: 10.1186/s12879-015-1275-3.

25. Satti H., McLaughlin M., Hedt-Gauthier B. et al. Outcomes of Multidrug Resistant

Tuberculosis Treatment with Early Initiation of Antiretroviral Therapy for HIV

Co-Infected Patients in Lesotho // PLoS One. – 2012; 7 (10): 46943.

26. Shivacoti R., Sharma D., Mamoon G. et al. Association of HIV infection with

extrapulmonary tuberculosis: a systemic review //Infection. – 2017; 1: 11–21. doi:

10.1007/s15010-016-0960-5

27. Sinshaw Y., Alemu Sh., Fekadu A., Gizachew M. Successful TB treatment

outcome and its associated factors among TB/HIV co-infected patients attending

Gondar University Referral Hospital, Northwest Ethiopia: an institution based

crosssectional study. // BMC Infectious Diseases. – 2017; 17: e132. DOI 10.1186/

s12879-017-2238-7

28. World Health Organization, Global tuberculosis report 2017. http://www.

who.int/tb/publications/global_report/en/(Accessed 2 August 2017).

Published

2025-02-18

How to Cite

Kholiev Bakhodir Oltibayevich. (2025). CURRENT TUBERCULOSIS A IN HIV-INFECTED PATIENTS . Ta’lim Innovatsiyasi Va Integratsiyasi, 39(2), 41-47. https://journal-web.uz/index.php/06/article/view/1473

Similar Articles

1-10 of 29

You may also start an advanced similarity search for this article.